CH 105 Section 001: Introductory Org Chem
Spring, 2010
4 Credit Hours
Primary Instructor: Bernard Scheiner
Core Designation: Natural Science
Office Hours: TWR 10:00-11:00 am or by appointment.
Four credit hours; three 50-minute lectures, one recitation/exam period, and one 3-hour laboratory per week. University core designation: NS. Prerequisite: CH 104 or equivalent.
Learning Outcomes: Students will learn to:
Chapter 12: Alkanes
1. Identify the number of bonds for carbon and other atoms in organic compounds.
2. Identify the functional groups in organic compounds.
3. Recognize and draw constitutional isomers.
4. Draw structures from structural formulas for alkanes.
5. Write the IUPAC and common names for alkanes and cycloalkanes.
6. Describe the physical properties of alkanes.
7. Write equations for the combustion and halogenations of alkanes.
Chapter 13: Alkenes, Alkynes, and Aromatic Compounds
1. Recognize the functional groups in alkenes, alkynes, and aromatic compounds.
2. Write the names for alkenes, alkynes and simple aromatic compounds.
3. Write structural formulas and names for cis-trans isomers of alkenes.
4. Recognize and describe the categories of organic reactions.
5. Write equations for halogenations, hydration and hydrogenation of alkenes and alkynes.
6. Describe the common reactions of aromatic compounds.
Chapter 14: Some Compounds with Oxygen, Sulfur, or a Halogen
1. Name and write the structural formulas for alcohols, phenols, ethers, thiols, and alkyl halides.
2. Classify alcohols as primary, secondary, or tertiary.
3. Describe the general properties of alcohols, phenols, and ethers.
4. Write equations for combustion, dehydration, and oxidation of alcohols.
Chapter 15: Amines
1. Name and write the structural formulas for amines.
2. Describe the ionization of amines in water.
3. Describe solubility of amines water.
Chapter 16: Aldehyde and Ketones
1. Name and write the structural formulas for aldehydes and ketones.
2. Describe the general properties some important aldehydes and ketones.
3. Write equations for oxidation of aldehydes and for the reduction of aldehydes and ketones.
4. Draw the structural formulas of hemiacetals and acetals produced from the addition of alcohols to aldehydes and ketones.
Chapter 17: Carboxylic Acids and Their Derivatives
1. Name and write the structural formulas for carboxylic acids, esters, and amides.
2. Describe the solubility and boiling points of carboxylic acids.
3. Write equations for the ionization of carboxylic acids in water.
4. Write equations for esterification and for the hydrolysis and saponification of esters.
5. Write equations for the formation and hydrolysis amides.
6. Recognize the structures of organic phosphoric esters.
Chapter 18: Amino Acids and Proteins
1. Draw the structures of amino acids (glycine, alanine, methionine, cysteine, glutamic acid, & lysine).
2. Draw the zwitterionic forms of amino acids at the isoelectric point and at pHs above and below the isoelectric point.
3. Recognize the property of “handedness” in simple molecules.
4. Write the structural formulas of dipeptides and tripeptides.
5. Identify the structural levels of proteins as primary, secondary, tertiary, and quaternary.
6. Describe the effects of denaturation on the structure of proteins.
Chapter 19: Enzymes and Vitamins
1. Describe the lock-and-key and induced-fit models of enzyme action.
2. Discuss the effect of changes in temperature, pH, and substrate concentration on enzyme action.
3. Describe the competitive, noncompetitive, and irreversible inhibition of enzymes.
4. Discuss feedback control and regulation of enzyme action by allosteric enzymes.
5. Describe in general the functions of vitamins and coenzymes
Chapter 21: The Generation of Biochemical Energy
1. Explain the role of ATP in biological reactions.
2. Compare the structures and function of the coenzymes NAD+, FAD and coenzyme A.
3. Describe the reactions of the citric acid cycle.
4. Explain how the electrons from NADH move along the electron transport chain to reduce O2 to H2O.
5. Describe the role of oxidative phosphorylation in ATP synthesis.
6. Identify the reactive oxygen species formed during metabolism and the harm that these can cause.
Chapter 22: Carbohydrates
1. Identify the common carbohydrates in the diet.
2. Distinguish between monosaccharides, disaccharides, and polysaccharides.
3. Identify the chiral carbons in a carbohydrate.
4. Label the Fischer projection for a monosaccharide as the D- or L-enantiomer.
5. Write Haworth structures for monosaccharides.
6. Describe the structural units and bonds in disaccharides and polysaccharides.
Chapter 23: Carbohydrate Metabolism
1. Describe the key reactions of glycolysis.
2. Describe the three possible fates of pyruvate.
3. Discuss the impact of ATP levels on glycogen metabolism.
4. Describe gluconeogenesis and the Cori cycle.
Chapter 24: Lipids
1. Describe the properties and types of lipids.
2. Write the structures of triacylglycerols obtained from glycerol and fatty acids.
3. Write structures of the products from hydrogenation, hydrolysis, and saponification of triacylglycerols.
4. Describe the role of phospholipids in cells and the transport of cholesterol.
5. Describe the lipid bilayer in cell membranes.
Chapter 26: Nucleic Acids and Protein Synthesis
1. Describe the structures of DNA and RNA.
2. Explain the process of DNA replication.
3. Describe the transcriptional process during the synthesis of mRNA.
4. Describe the translation of codons into the amino acid sequence of proteins.
Tentative Lecture Schedule
|
Week |
Lecture Topics |
Lab |
Notes |
|
|
|
|
|
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January 4 - 8 |
No Classes |
No Labs |
ROLL TIDE! |
|
January 11 - 15 |
Chapter 12: Alkanes |
Check-in |
|
|
January 18 - 22 |
Chapter 13: Alkenes/Alkynes/Aromatic Cmpds |
No Labs |
Monday: MLK Day |
|
January 25 - 29 |
Chapter 14: Oxygen, Sulfur & Halogen Cmpds |
Alkanes |
|
|
February 01 - 05 |
Finish Chapter 14 |
Hydrocarbons |
Thursday: Exam 1 |
|
February 08 - 12 |
Chapter 15: Amines
Chapter 16: Aldehydes & Ketones |
Alcohols |
|
|
February 15 – 19 |
Finish Chapter 16
Chapter 17: Carboxylic Acids & Derivatives |
Aldehydes & Ketones |
|
|
February 22 - 26 |
Finish Chapter 17 |
Carboxylic acids |
Thursday: Exam 2 |
|
March 01 - 05 |
Chapter 18: Amino Acids & Proteins |
Amines & Amides |
|
|
March 08 - 12 |
Chapter 19 Enzymes
Chapter 21: Energy and Biochemical Reactions |
Amino acids |
|
|
March 15 – 19 |
No Classes |
No Labs |
Spring Break |
|
March 22 - 26 |
Finish Chapter 21 |
Enzymes |
Thursday: Exam 3 |
|
Mar 29 - Apr 02 |
Chapter 22: Carbohydrates |
Carbohydrates |
|
|
April 05 - 09 |
Chapter 23: Carbohydrate Metabolism |
No Labs |
Friday: Honors Day |
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April 12 - 16 |
Chapter 24: Lipids
Chapter 26 Nucleic Acids |
Lipids |
|
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April 19 - 23 |
Finish Chapter 26 |
DNA Extraction |
Thursday: Exam 4 |
|
April 26 - 30 |
Review for Final Exam |
Check-out |
Dead Week |
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May 3 - 7 |
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Final Exams |
There will be four one-hour exams (100 pts each). Each exam will focus on the material of two or three chapters. A cumulative final exam (100 pts) is scheduled during the prescribed time. The lowest grade of the four one-hour exams will be dropped. The final exam can be skipped with an average exam grade >92%.
Exam 1 (Chapters 12, 13 & 14) February 4 (Thursday)
Sec 001 5:00 pm, Shelby 1004
Sec 002 5:00 pm, Shelby 1093
Sec 003 6:30 pm, Shelby 1093
Exam 2 (Chapter 15, 16 & 17) February 25 (Thursday)
Sec 001 5:00 pm, Shelby 1004
Sec 002 5:00 pm, Shelby 1093
Sec 003 6:30 pm, Shelby 1093
Sec 001 5:00 pm, Shelby 1004
Sec 002 5:00 pm, Shelby 1093
Sec 003 6:30 pm, Shelby 1093
Exam 4 (Chapters 22, 23, 24 & 26) April 22 (Thursday)
Sec 001 5:00 pm, Shelby 1004
Sec 002 5:00 pm, Shelby 1093
Sec 003 6:30 pm, Shelby 1093
May 06 (Thursday)
Sec 002 08:00 am, Shelby 1093
Sec 003 11:30 am, Shelby 1093
May 07 (Friday)
Sec 001 11:30 am, Shelby 1004
Homework will be assigned using MasteringGOBChemistry. Homework will NOT be accepted late unless excused by the instructor (for illness, etc). The homework grade will be determined as the percentage of successfully completed exercises and will count 100 pts toward the course grade.
Students are required to register for a laboratory section for this course. The grading and policies of the laboratory are set by the Laboratory Coordinator (Ms. Erica Livingston). The laboratory will count for 100 pts toward the course grade. Note that absences from three (3) or more labs will result in failure of the course.
The course grade will be determined from the sum of:
3 highest exam grades 300 pts total
final exam grade 100 pts
homework grade 100 pts
laboratory grade 100 pts
total 600 pts
The total points earned will be divided by 6, and grades will be assigned using the scale below:
Score Grade
100-90 A+ / A / A-
89-80 B+ / B / B-
79-70 C+ / C / C-
69-60 D+ / D / D-
59-0 F
Any scaling of grades will be done at the end of the semester and at the discretion of the instructors. Because this is out of your control, DO NOT RELY ON A SCALE BEING APPLIED TO YOUR SCORES!
Attendance at examinations is mandatory unless previous arrangements are made with the instructor. If an exam is missed without prior arrangements being made, a grade of zero will be assigned unless the absence is determined by the instructor to be excused. Excused absences will be granted only with a legitimate, documented excuse (such as illness or death) and should be obtained as early as possible. In these cases, make-up exams will typically not be given, but other arrangements can be made (using drop exam, double-counting of final, etc).
Extensions for homework assignments will only be granted with legitimate, documented excuse (such as illness or death) and should be obtained as early as possible.
Note that absences from three (3) or more labs will result in failure of the course.
Attendance at all lectures and recitations is expected. While attendance at recitations is not required, it is strongly encouraged. Recitations will meet Thursday evenings without exams. These meetings will concentrate on problem solving.
Web-based Homework:
Access to the Prentice Hall MasteringGOBChemistry system is required and can be purchased bundled with the textbook or individually.
Laboratory Manual:
Catalyst: The Prentice Hall Custom Laboratory Program for Chemistry University of Alabama Chemistry CH104/105 Pearson Custom Publishing: Boston, MA, 2008 (ISBN 0-536-11169-3)
Extra credit may be offered to the entire class at the discretion of the instructor. In no case will extra credit be offered to individual students.
All students in attendance at the University of Alabama are expected to be honorable and to observe standards of conduct appropriate to a community of scholars. The University expects from its students a higher standard of conduct than the minimum required to avoid discipline. Academic misconduct includes all acts of dishonesty in any academically related matter and any knowing or intentional help or attempt to help, or conspiracy to help, another student.
The Academic Misconduct Disciplinary Policy will be followed in the event of academic misconduct.
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